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Like adults, pediatric patients should be carefully observed with frequent measurements of blood pressure, weight, height, intraocular pressure, and clinical evaluation for the presence of infection, psychosocial disturbances, thromboembolism, peptic ulcers, cataracts, and osteoporosis

It promotes neuron survival by activating anti-apoptotic pathways through its TrkB receptor

Overexpression of NOX4 inhibits mitochondrial respiration by reducing mitochondrial protein complexes, promoting mitochondrial ROS production, and thus inducing ferroptosis in astrocytes

Yang Y., Yan D., Cheng H., et al., Discovery of Novel 1,2,4Triazole Derivatives as Xanthine Oxidoreductase Inhibitors With Hypouricemic Effects, Bioorganic Chemistry 129 (2022): 106162, 10.1016/j.bioorg.2022.106162

What separates the rungs is not cadence but the evidence standing behind each one, read low to high